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What is CRISPR?

Added: 24 October 2026

CRISPR is a family of genome-editing methods adapted from natural bacterial defense systems.

How it works and what the evidence shows

Core idea A guide RNA can direct a suitable Cas protein to a target sequence. A cut triggers cellular repair, which may create a change; outcomes depend on the enzyme and design. Evidence and research Researchers use CRISPR to test gene function and build model organisms. Some medical uses are investigated for particular conditions, but it is not a ready cure for every disease.

Uses and limitations

Why it matters Off-target changes, unexpected repair and delivery problems all need assessment. Heritable interventions also raise ethical and social questions. Common misunderstandings CRISPR does not rewrite DNA perfectly. Results depend on the target, cell and method and require sequencing and proper controls.

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Revision history

24 October 2026 — Article added.